STOP

Research Goal

We are collaborating with the University of Manchester and Head Instruments Oy to design novel means for Parkinson's disease handling. We leverage accesibility and computing power of mobile devices and apply them into use for long-term and distant observation of Parkinson's patients.

STOP: Sentient Tracking of Parkinson’s

Effective monitoring of patients is technically challenging with wearables due to: 1) battery life is limited to a few hours when sampling and processing data continuously; 2) it is not feasible to process large amounts of sensor data on a wearable (e.g., a smartwatch). Instead of wearables, we leverage widely available technology such as smartphones, and Internet-of-Things (IoT) sensors, and augment their sensing capabilities with user-centric machine learning to create an infrastructure that links medication alerts to movement phenomena in real-time, to improve medication dosing for Parkinson’s patients and to unobtrusively monitor the progression of Parkinson’s Disease (PD).

STOP makes possible PD real-time symptom tracking, empowers DBS (Deep Brain Stimulation) patients with intelligent micro-adjustments of neurostimulators’ electrical stimulation, and provides medication dosing awareness and reminders for improving medication compliance. STOP provides valuable PD information for clinicians (e.g., a personal understanding of medication dosing lasting effects, the impact of PD symptoms in daily tasks, potential changes in mobility and social behaviour), thus potentially improving the efficiency of PD health services. STOP can minimize travel: clinically relevant data can be gathered and delivered remotely to clinicians and health researchers, allowing them to intervene, study and better understand PD; monitor PD unobtrusively over clinically relevant time periods: sensor data is gathered autonomously over long periods of time to better understand the manifestation of PD symptoms during day-to-day activities and inform future interventions and guidelines; provide clinically predictive modelling of medication need: intelligent personal modelling of users will allow for tailored PD support, particularly when PD symptoms are troublesome and require medication and DBS intervention.

Following AWARE’s plugin-based architecture, STOP will be a scalable, battery-conscious, cost-effective PD monitoring solution that uses commercially available smartphones and IoT sensors to collect and judiciously send data to a cloud infrastructure to improve PD patients’ quality of life. STOP will transform the care of PD by enabling an ecosystem of support involving patients, families, caregivers, clinicians and health researchers, working together. By monitoring the progression of PD, clinicians can better understand the effects of the medication, users’ lifestyle and individual Parkinson’s progression. Effective monitoring, analysis of movements and predictive modelling can be used by clinicians to send real-time medication alerts, improve medication adherence, and monitor PD patients’ quality of life from afar, also applicable for other neurological disorders, such as dementia, Alzheimer’s and Huntington’s.

STOP: mobile application

STOP is a toolkit for PD observation available both for Android and iOS. It allows to colleсt symptoms snapshots and medication regimen adherance continuosly.

The application components have been evaluated in three trial studies; one trial was month-long in-the-wild and performed in Finland and in the UK.

Accelerometer game

Assesses level of tremor by collecting sensors data. Allows to edit ball speed, UI size, game time for experimental reusability.

Touch screen tasks

Measures effect of dexterity and dyskinesia via Archimedian spiral and square-shape drawing excercises.

Myo armband

Wearable device used for uderstanding muscle rigidity by colecting motion and EMG samples.

User profile

Self-reporting of medication plan and general symptoms (UPDRS). Requested to be filled only on first application run.

Medication journal

Retrospective log of every medication intake time. Supports manual input and natural voice recognition, e.g. "two hours ago".

Daily survey

Query about general health stated for the previous day. Shows up once per day between 10:00 and 11:00 AM.

User-centered design

STOP is designed to be accessbile for patients: notification reminders, big-shaped buttons, voice input, feedback acceptance.

Multilanguage support

Available in English and Finnish. If you want to help, translate this file to your own language and send it to us.

Want to join our study?

Simply tap the button here on your Android device to join.

You do not need constant internet connection for the application use: it stores data locally and syncs it to remote server once per half an hour.

Publications